FINAL RECORD: 20-14
| Date | Opponent | Score | Result |
| 9/10/99 | William Paterson* | 3-0 (15-5, 15-4, 15-7) | W |
| 9/11/99 | Haverford* | 3-0 (15-11, 15-7, 15-7) | W |
| at Vassar* | 0-3 (8-15, 14-16, 12-15) | L | |
| Kean (NJ)* | 3-0 (15-9, 15-5, 15-7) | W | |
| 9/17/99 | at Western Connecticut$ | 3-2 (12-15, 15-11, 15-11, 5-15, 15-13) | W |
| 9/18/99 | St. Anselm$ | 0-3 (5-15, 6-15, 12-15) | L |
| Hunter$ | 3-1 (9-15, 15-13, 15-6, 15-10) | W | |
| 9/24/99 | Amherst% | 1-3 (5-15, 15-7, 2-15, 6-15) | L |
| Gordon% | 2-3 (15-8, 16-14, 7-15, 15-17, 12-15) | L | |
| 9/25/99 | Smith% | 3-1 (15-4, 15-9, 12-15, 15-9) | W |
| Skidmore% | 2-3 (3-15, 15-6, 13-15, 15-9, 16-18) | L | |
| 9/28/99 | Eastern Connecticut | 1-3 (15-3, 10-15, 9-15, 7-15) | L |
| 10/1/99 | Trinity^ | 3-2 (15-10, 11-15, 13-15, 15-9, 15-8) | W |
| 10/2/99 | St. Joseph (CT)^ | 3-1 (11-15, 15-4, 15-10, 15-6) | W |
| Smith^ | 3-1 (13-15, 15-7, 15-2, 15-12) | W | |
| 10/6/99 | Connecticut College | 3-0 (15-4, 15-5, 15-2) | W |
| 10/8/99 | at Eastern Connecticut@ | 3-2 (10-15, 15-13, 12-15, 15-12, 15-9) | W |
| 10/9/99 | Wheaton@ | 3-0 (15-13, 15-7, 16-14) | W |
| Bates@ | 1-3 (11-15, 7-15, 15-9, 6-15) | L | |
| Middlebury@ | 0-3 (10-15, 8-15, 3-15) | L | |
| 10/15/99 | at Amherst | 1-3 (6-15, 2-15, 15-12, 3-15) | L |
| 10/16/99 | Williams (at Amherst) | 0-3 (5-15, 5-15, 4-15) | L |
| Bowdoin (at Amherst) | 3-1 (15-9, 8-15, 15-3, 15-3) | W | |
| 10/20/99 | Western Connecticut | 3-0 (15-12, 15-11, 15-4) | W |
| 10/23/99 | Trinity& | 3-0 (16-14, 15-10, 15-12) | W |
| at Coast Guard& | 3-1 (15-8, 14-16, 15-7, 15-11) | W | |
| Roger Williams& | 3-0 (15-6, 15-3, 15-3) | W | |
| 10/28/99 | at Mount Holyoke | 3-2 (15-3, 6-15, 4-15, 15-9, 15-8) | W |
| 10/30/99 | Amherst (at Williams) | 1-3 (12-15, 7-15, 15-10, 6-15) | L |
| at Williams | 0-3 (14-16, 12-15, 1-15) | L | |
| 11/5/99 | Williams# | 1-3 (15-12, 13-15, 11-15, 10-15) | L |
| 11/6/99 | Hamilton# | 3-0 (15-5, 15-12, 15-12) | W |
| at Trinity# | 3-1 (12-15, 15-8, 15-5, 15-10) | W | |
| 11/12/99 | M.I.T.+ | 1-3 (15-11, 1-15, 12-15, 10-15) | L |
| # - Name | MP/MS/GP | Kills | Set Assists | Service Aces | Digs | Blocks: Solo/Asst/Errors |
| #13 - Eliza Allen '03 | 34/34/128 | 322 | 11 | 0 | 36 | 45/127/6 |
| #10 - Laurie Bonilla '03 | 14/0/18 | 2 | 23 | 2 | 23 | 0/0/0 |
| #11 - Christina Fucci '02 | 32/32/117 | 60 | 1144 | 41 | 141 | 9/48/10 |
| #8 - Jen Graeff '02 | 22/1/39 | 48 | 6 | 5 | 63 | 1/6/1 |
| #6 - Carolina Griggs '02 | 11/0/16 | 9 | 3 | 3 | 33 | 1/4/0 |
| #5 - Elise House '01 | 34/34/118 | 158 | 32 | 19 | 134 | 4/57/6 |
| #3 - Anne Johnson '01 | 34/0/128 | 2 | 16 | 59 | 205 | 0/0/0 |
| #14 - Alexis Keeler '02 | 34/34/128 | 248 | 21 | 96 | 345 | 25/83/10 |
| #4 - Vida Long '03 | 4/0/4 | 0 | 0 | 0 | 0 | 0/0/0 |
| #17 - Shannon Pao '03 | 6/2/14 | 16 | 90 | 2 | 20 | 3/4/0 |
| #2 - Jessica Rooney '00 | 33/32/119 | 286 | 29 | 67 | 296 | 3/31/7 |
| #12 - Sarah Synakowski '00 | 34/31/112 | 295 | 16 | 18 | 135 | 16/43/3 |
| #7 - Christine Szczepanski '00 | 32/4/91 | 61 | 13 | 42 | 138 | 4/13/2 |
| Wesleyan Totals | 34/34/128 | 1507 | 1404 | 354 | 1569 | 111/416/45 |
| Opponent Totals | 34/34/128 | 1244 | - | 254 | 1941 | - |