Janice R. Naegele
Selected Publications
Hartman, N., Grabel L.B., and Naegele, J.R.
(accepted for publication) Migration of Transplanted Neural Stem
Cells in Models of Neurodegenerative Diseases. Stem Cells and
Regenerative Medicine. Springer Science (Humana Press).
Naegele, J.R. and Maisano X. (2010) Gene and Stem Cell Therapies for Treating Epilepsy. Epilepsy: Mechanisms, Models, and Translational Perspectives, Dekker M, Inc. (CRC Press). Rho JM, Sankar R, Stafstrom CE (Eds.). (In Press).
Naegele, J.R. (2009) Epilepsy and the Plastic Mind. Epilepsy Currents 9.6. (In press).
Liu J, Naegele J.R,, and Lin, S.L. (2009) DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation. Brain Research. In Press.
Maisano, X., Carpentino, J., Becker, S., Lanza, R., Aaron, G., Grabel, L., and Naegele, J.R. (2009) Embryonic stem cell-derived neural precursor graft for treatment of temporal lobe epilepsy. Neruotherapeutics 6(2): 263-277.
Cho,i Y.-S., Cho, H.-Y., Hoyt, K.R., Naegele, J.R., and Obrietan, K. (2008) IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus. Gilia 56(7): 791-800.
Carpentino, J.E., Hartman, N., Grabel, L.B., and Naegele, J.R. (2008) Region specific differentiation of embryonic stem cell-derived neural progenitor transplants in the adult mouse hippocampus following seizures. J. Neuroscience Research 86(3): 512-524.
Choi, Y-S., Lin, S.L., Lee, B.,
Kurup, P., Cho, H-Y.,and Naegele, J.R., Lombroso, P.J., Obrietan, K.
(2007)
Status epilepticus-induced somatostatinergic hilar interneuron degeneration
is regulated by striatal enriched protein tyrosine phosphatase.
J. Neuroscience
27(11): 2999-3009.
Naegele, J.R. (2007)
Neuroprotective strategies to avert seizure-induced
neurodegeneration in epilepsy. Epilepsia 48(Supplement 2): 107-117.
Navarro-Quiroga, I., Hernandez-Valdes, M., Lin, S.L.,and Naegele, J.R.
(2006)
Postnatal cellular contributions of the hippocampus subventricular zone to
the dentate gyrus, corpus callosum, fimbria, and cerebral cortex. J.
Comp. Neurol. 497(5): 833-845.
Neema, M., Navarro-Quiroga, I., Chechlacz, M., Gilliams-Francis, K., Liu, J., LaMonica, K., Lin, S., and
Naegele J.R. (2005) DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures.
Hippocampus 15(8):1057-1071.
Narasimhaiah, R., Tuchman, A., Lin, S.L., and Naegele, J.R. (2005) Oxidative damage and defective DNA repair is linked to apoptosis of migrating neurons and progenitors during cerebral cortex development in Ku70-deficient mice.
Cerebral Cortex 15(6): 696-707.
Gilliams-Francis, K.L., Quaye, A., and Naegele, J.R. (2003)
PARP cleavage, DNA fragmentation, and pyknosis during excitotoxin-induced neuronal death.
Exp. Neurol. 184(1): 359-372.
Chechlacz, M. and Naegele, J. (2002) Genetics of childhood disorders: XL. Stem cell research, part 4: neural horticulture.
J. Am. Acad. Child Adolesc. Psychiatry 41(7):882-5.
Naegele, J.R. and Lombroso, P.J. (2001) Genetics of central nervous system developmental disorders.
Child Adolesc. Psychiatr. Clin. N. Am. 10(2):225-39.
Chechlacz, M., Vemuri, M., and Naegele, J.R. (2001) Role of DNA-Dependent Protein Kinase in Neuronal Survival.
J. Neurochem. 78(1):141-54.
Vemuri, M., Schiller, E., and Naegele, J.R. (2001) Elevated DNA Double Strand Breaks and Apoptosis in the CNS of scid Mutant Mice.
Cell Death Differ. 8(3): 245-255.
Upender, M.B. and Naegele, J.R. (1999)
Activation Of Microglia During Developmentally Regulated Cell Death In The Cerebral Cortex.
Dev. Neurosci. 21(6): 491-505
Naegele, J.R. and Lombroso, P.J. (1998) Apoptosis in the cerebral cortex.
J. Am. Acad. Child Adoles. Psychiatry. 37(8): 890-892.
Upender, M.B., Dunn, J.A., Wilson, S.M., and
Naegele, J.R. (1997)
Immunoglobulin molecules are present in early-generated
neuronal populations in the rat cerebral cortex and
retina. J. Comp. Neurosci. 384: 271-282.
Bult, A., Zhao, F., Dirkz, R., Sharma, E., Lukacsi, E., Solimena, M.,
Naegele, J.R., and Lombroso, P. (1996)
STEP61: A new member of a family of brain-enriched PTPs is targeted to the endoplasmic reticulum.
J. Neurosci. 16: 7821-7831.
Upender, M. and Naegele, J.R. (1996) Preparation and growth of embryonic neurons in tissue culture. In: Neuroscience Methods: The Undergraduate Laboratory Experience, (D.G. Blackburn, ed.), Trinity College Press, Hartford, CT.
Raghunathan, A., Matthews, G.A., Lombroso, P.J., and
Naegele, J.R. (1996) Transient compartmental expression of a protein tyrosine phosphatase in the developing striatum.
Develop. Brain Res. 91(2): 190-199.
Spicer, S.S., Naegele, J.R., and Schulte, B.A. (1996)
Differentiation Of Glycoconjugates Localized To Sensory Terminals And Selected Sites In Brain.
J. Comp. Neurol. 365(2): 217-231.
Dunn, J.A., Kirsh, J., and Naegele, J.R. (1995)
Transient immunoglobulin-like molecules are present in
the subplate zone and cerebral cortex during postnatal
development. Cerebral Cortex 5: 494-505.
Boulanger, L., Lombroso, P.L., Ragahunathan, A., During, M.J., Wahle, P.R., and
Naegele, J.R. (1995)
Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase.
J. Neurosci. 15: 1532-1544.
Naegele, J.R. and Lombroso, P.J. (1994)
Protein tyrosine phosphatases in the Central Nervous System.
Critical Reviews in Neurobiology 9(1): 105-114.
During, M.J., Naegele, J.R., O'Malley, K., and Geller, A.I. (1994) Long term behavioral recovery in the rat model of Parkinson's Disease by intrastriatal injection of a HSV-1 vector expressing tyrosine hydroxylase.
Science 266: 1399-1403.
Wahle, P., Lubke, J., and Naegele, J.R. (1994)
Inverted pyramidal neurons and interneurons in cat cortical subplate zone are labeled by monoclonal antibody SP-1.
Eur. J. Neurosci. 6: 1167-1178.
Lombroso, P.J.,
Naegele, J.R., Sharma, E., and Lerner, M. (1993) A Protein Tyrosine Phosphatase Expressed Within Dopaminoceptive Neurons Of The Basal Ganglia And Related Structures. J. Neurosci. 113(7): 3064-3074. Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06536.
Barnstable, C.J., Kosaka, T., Naegele, J.R., and Arimatsu, Y. (1992) Molecular Properties of GABAergic Local-Circuit Neurons In: The Mammalian Visual Cortex.
Prog. Brain Res. 90:503-522.
Naegele, J.R. and Barnstable, C.J. (1991)
A Carbohydrate Epitope Defined By Monoclonal Antibody VC1.1 Is Found On N-CAM and Other Cell Adhesion Molecules. Brain Res. 559(1):118-129.
Naegele, J.R., Barnstable, C.J., and Wahle, P.R. (1991)
Expression of a unique 56 kDa polypeptide by neurons in the subplate zone of the developing cerebral cortex. Proc. Natl Acad. Sci. (USA) 88: 330-334.
Zaremba, S.,
Naegele, J.R., Barnstable, C.J. and Hockfield, S. (1990)
Neuronal Subsets Express Multiple High-Molecular-Weight Cell-Surface Glycoconjugates Defined By Monoclonal Antibodies Cat-301 and VC1.1.
J. Neurosci. 10(9): 2985-2995.
Naegele, J.R. and Katz, L.C.
(1990)
Cell Surface Molecules Containing N-Acetylgalactosamine Are Associated With Basket Cells And Neurogliaform Cells In Cat Visual Cortex.
J. Neurosci. 10(2): 540-557.
Naegele, J.R. and Barnstable, C.J. (1989)
Molecular Determinants Of GABAergic Local-Circuit Neurons In The Visual Cortex.
Trends Neurosci. 12(1): 28-34.
Naegele, J.R., Jhaveri, S. and Schneider, G.E.
(1988)
Sharpening Of Topographical Projections And Maturation Of Geniculocortical Axon Arbors In The Hamster.
J. Comp. Neurol. 277(4): 593-607.
Naegele, J.R., Arimatsu, Y., Schwartz, P. and Barnstable, C.J. (1988)
Selective staining of a subset of GABAergic neurons in cat visual cortex by monoclonal antibody VC1.1.
J. Neurosci. 8(1): 79-89.
Arimatsu, Y., Naegele, J.R. and Barnstable, C.J. (1987) Molecular Markers Of Neuronal Subpopulations In Layers 4, 5, And 6 Of Cat Primary Visual Cortex.
J. Neurosci. 7(4): 250-263.
Birch E.E., Gwiazda, J., Bauer, J.A.,
Naegele, J.R.,
and Held, R. (1983)
Visual acuity and its meridional variations in children
aged 7-60 months. Vision Res. 23(10):
1019-1024.
Naegele, J.R. and Held, R. (1982)
The Postnatal Development Of Monocular Optokinetic Nystagmus In Infants.
Vision Res. 22(3): 341-346.