Faculty by Research Area

Professor of Biology
Shanklin Laboratory 302
860-685-3518

acburke@wesleyan.edu

AB New York University
MA Harvard University
PHD Harvard University

Personal Web Site:
http://acburke.faculty.wesleyan.edu/

Scholarly Keywords:
Development and evolution of vertebrates

Lab URL:
http://burkelab.research.wesleyan.edu/

Publications:
http://acburke.faculty.wesleyan.edu/

Professor of Biology
Shanklin Laboratory 306
860-685-3461

Professor, Neuroscience & Behavior
860-685-3461

sdevoto@wesleyan.edu

BA Haverford College
PHD Rockefeller University
DU

Personal Web Site:
http://sdevoto.web.wesleyan.edu/

Scholarly Keywords:

Muscle Fiber Type Development, Muscle Growth, Somite Patterning, myogenic stem cells, zebrafish

Lab URL:
http://sdevoto.web.wesleyan.edu/

Lauren B. Dachs Professor of Science and Society
Hall-Atwater Laboratories 209
860-685-3238

Professor of Biology
Hall-Atwater Laboratories 209
860-685-3238

lgrabel@wesleyan.edu

BA Brandeis University
MAA Wesleyan University
PHD University of California, San

Personal Web Site:
http://lgrabel.web.wesleyan.edu/Lab%20Homepage/main2.html

Scholarly Keywords:
Neurogenesis of embryonic stem cells, Hedgehog signaling in angiogenesis, cell-extracellular matrix interactions and cell migration.

Assistant Professor of Biology
Hall-Atwater Laboratories 212
860-685-2963

rijohnson@wesleyan.edu

BS University of Witwatersrand
PHD Cambridge University

Academic Associations:

The American Society of Cell Biology

Genetics Society of America

Lab URL:
http://johnsonlab.research.wesleyan.edu

Professor of Biology
Hall-Atwater Laboratories 254
860-685-3232

Director, Center for Faculty Career Development

Professor, Neuroscience & Behavior
860-685-3232

jnaegele@wesleyan.edu

BA Mount Holyoke College
PHD Massachusetts Institute Techno

Personal Web Site:
http://naegelelab.research.wesleyan.edu/

Research Interests:

Deficits in GABAergic interneuron populations have been found to underly a number of neuropsychiatric disorders as well as epilepsy. In our research, we study the origins and functions of forebrain interneurons in rodent models of Fragile X syndrome and epilepsy. We are also investigating GABAergic interneuron replacement in temporal lobe epilepsy using different stem cell sources - fetal telencephalon and mouse and human embryonic stem cells. We have discovered that GABAergic progenitor grafts suppress spontaneous seizures for extended periods of time in the rodent brain. We have also demonstrated long-term survival, migration, and integration of ES cell-derived neurons in the adult hippocampus. The questions we are now pursuing are: 1) what are the molecular mechanisms regulating functional integration GABAergic interneuros; 2) what are the major differences in neural repair capacity of GABAergic neural progenitors derived from ES cells vs. fetal brain for treating temporal lobe epilepsy?

Scholarly Keywords:

Neural stem cells, mouse models of epilepsy, electroencephalography (EEG recordings), immunohistochemistry, neurodegeneration, apoptosis, gene expression, synapse formation, adult neurogenesis

Academic Associations:

International Society for Stem Cell Research; Society for Neuroscience; AAAS American Epilepsy Society; American Epilepsy Society

Grants:

Connecticut Stem Cell Initiative

Lab URL:
http://naegelelab.research.wesleyan.edu/

Publications:
http://naegelelab.research.wesleyan.edu/publications/

Editorial Boards:

Epilepsy CurrentsFrontiers in NeurogenesisBrain and Development

Board Memberships:

Epilepsy Foundation of Connecicut

Professor of Biology
Hall-Atwater Laboratories 112
860-685-2402

Director, Hughes Program in the Life Sciences
860-685-2402

mweir@wesleyan.edu

BS University of Sussex
PHD University of Pennsylvania

Scholarly Keywords:
proteomics; molecular genetics; bioinformatics.

Grants:
National Institutes of Health

Lab URL:
http://weirlab.research.wesleyan.edu/

Publications:
http://weirlab.research.wesleyan.edu/publications/