Chemistry

About the Major

Department/Program Description.

Chemistry is the science of molecules. Scientific, medical, and technological phenomena ultimately are understood in terms of molecular structure and interactions. Understanding chemistry is essential to effective work in all sciences, and some knowledge of chemistry is useful in such fields as law, government, business, and art. Many aspects of our high-technology society can be understood better from the viewpoint of chemistry.

The following are typical important chemical problems: the structure of DNA, the molecular details of the resistance of bacteria to penicillin, the chemistry of biofuel production, the synthesis of new molecules that might be expected to have medical applications, the consequences of putting electrons and photons into molecules, the details of what happens as two molecules collide, the fundamental basis of the energies of molecules, and the synthesis of nanomaterials. These are all areas of research by Wesleyan faculty and their undergraduate and graduate coworkers.

Courses for Non-Majors.
  • Nonscientists are encouraged to consider CHEM117, 118, 119, 120, 198, or CHEM141/142 as part of their program to meet NSM requirements. CHEM117 covers basic aspects of human biochemistry and molecular biology. CHEM118 provides an interdisciplinary view of the DNA molecules and their impact on society at large. CHEM119 studies the basic chemistry of several diseases, including AIDS, cancer, bacterial infections, and the drugs used to treat them, as well as psychotherapeutic drugs. CHEM120 covers basic chemical principles and then shows how these principles relate to important issues in the real world, such as global warming, alternative energy, genetic engineering, and the treatment of diseases. CHEM198 gives an overview of the modern criminal forensics procedures with hands-on experience. CHEM141/142 is an introduction to chemistry that includes quantitative material. CHEM141 can be taken as a single-semester course toward the NSM requirements and can be taken by students who have had no high school chemistry.
  • Scientists majoring in areas other than chemistry can prepare themselves better for work in their discipline by having a grounding in chemistry, which will enable them to understand molecular phenomena. The Chemistry Department offers two yearlong tracks of Introductory Chemistry, CHEM141/142 or 143/144. The CHEM143/144 sequence, requiring some prior chemistry and calculus, provides a more sophisticated introduction and represents a better preparation for science majors. The CHEM141/142 sequence requires no previous exposure to chemistry or calculus and emphasizes environmental and biological applications. CHEM152 Introductory Chemistry Laboratory is taken concurrently with CHEM143 in the fall semester or with CHEM142 or 144 in the spring semester. Principles of Organic Chemistry I/II (CHEM251/252) normally follow Introductory Chemistry. The laboratory courses, CHEM257 General Chemistry Laboratory and CHEM258 Organic Chemistry Laboratory, are usually taken concurrently with CHEM251/252, respectively. The two courses, Introductory Chemistry and Organic Chemistry, plus the laboratory sequence, CHEM152, 257, 258, are required for admission to medical, dental, and veterinary schools.
Admission to the Major.

Students who anticipate the possibility of majoring in chemistry should, if possible, take CHEM143/144 as first-year students. The program for majors is described in detail below.  A student whose interest in biochemistry arises from a desire to understand biological systems at the molecular level may choose to study biochemistry as a chemistry major. (See Biological chemistry track below.)

Major Requirements.

To major in chemistry, a student should complete a year of Introductory Chemistry (CHEM141/142, or, preferably, CHEM143/144, and the associated lab CHEM152), unless the student has been given Advanced Placement credit. In addition, a year of organic chemistry (CHEM251/252), the concurrent laboratories (CHEM257/258), and a year of physical chemistry (CHEM337/338) are required. One year of advanced laboratory is required (CHEM375/376), the Integrated Chemistry Laboratory. Chemistry majors are also required to register for and attend two semesters of Chemistry Symposia (CHEM521/522). The major is completed by electing a total of at least three credits from 300-level courses (other than CHEM337/338). All courses other than seminars that are required for the chemistry major must be taken under a letter-grading mode (A-F). One of the three 300-level electives may be replaced by two semesters of research (CHEM409/410 Senior Thesis, or CHEM423/424 Undergraduate Advanced Research Seminar). Other seminars or journal clubs cannot be counted as electives. All chemistry majors are encouraged to do research with a faculty member, including during one or more summers. Financial support for summer research is generally available.

One year of calculus (MATH117/118 or MATH121/122 or Advanced Placement credit with a score of 4 or 5) and one year of physics (PHYS111/112 or PHYS113/116 or Advanced Placement credit with a score of 4 or 5) are also required for the major. Students who do not study inorganic chemistry in CHEM144, either through exemption or because they have satisfied the introductory chemistry requirement with CHEM141/142, must select CHEM361 or CHEM363 as one of their 300-level electives.

Before or during the second semester of the sophomore year, a student interested in majoring in chemistry should consult with the chair of the Chemistry Department or the departmental advisors for specific areas of chemistry (analytical, biochemistry, inorganic, organic, and physical) concerning a suitable program of study. If the student does opt for a chemistry major, these people may also assist in the choice of a major advisor for the student. Students who intend to be multiple majors are strongly advised to consult with their chemistry advisors at the beginning of their junior year to plan their chemistry program.

A chemistry major planning graduate work in chemistry ordinarily takes at least one additional 300-level chemistry course (excluding CHEM337/338) and two semesters of undergraduate research, CHEM409/410 or CHEM421/422. When feasible, an intensive continuation of research during at least one summer is encouraged. The preparation of a senior thesis based on this research (CHEM409/410 Senior Thesis, or CHEM423/424 Undergraduate Advanced Research Seminar) provides extremely valuable experience and is strongly recommended. Graduate courses may be elected with permission. A chemistry major planning to attend medical school, teach in a secondary school, or do graduate work in such fields as biochemistry, geochemistry, environmental science, or chemical physics may request permission from the departmental curriculum committee to replace one of the elective credits in the concentration program with an appropriate course offered by another science or mathematics department. A similar substitution may be requested when appropriate as part of an interdepartmental major. Independent research is encouraged.

A solid mathematical background is important to those students who plan to do graduate work in chemistry. Such students should also try to take PHYS113 and 116 prior to their junior year. MATH221 and 222 are recommended to those whose interests lie in physical chemistry.

Biological Chemistry Track. The Chemistry Department recognizes that a number of students each year are interested in a major program containing both a strong biology or biochemistry component and somewhat less emphasis on chemistry than the standard chemistry major. In response to this interest, the Chemistry Department now offers a biological chemistry track. This track would, for example, be an excellent preparation for medical school or graduate school in biochemistry and biophysics. (Students interested in chemistry as a profession are advised to take the standard chemistry major track, which provides a better preparation for graduate school in chemistry.)

To begin a major in this track, a student should complete a year of Introductory Chemistry (CHEM141/142, or, preferably, CHEM143/144, and the associated laboratory, CHEM152), unless the student has been given Advanced Placement credit. In addition, one year of organic chemistry (CHEM251/252), the concurrent laboratories (CHEM257/258), and a semester of biology (BIOL/MB&B181) are required. One year of advanced laboratory (CHEM375/376, Integrated Chemistry Laboratory) and two semesters of the Chemistry Symposia (CHEM521/522) are also required. MB&B395/CHEM395 Structural Biology Laboratory may be substituted for one semester of CHEM375/376. Also required are Biochemistry (CHEM383) and Physical Chemistry for the Life Sciences (CHEM381). The two-semester physical chemistry sequence, CHEM337/338, can be substituted for CHEM381 with the second semester of this sequence then counted as one of the three electives. Students who have been exempted from CHEM144 must take CHEM361 Advanced Inorganic Chemistry to gain familiarity with inorganic chemistry. The three electives normally required for chemistry majors should be taken from the following: CHEM301 Molecular and Cellular Biophysics, CHEM/MB&B321 Biomedicinal Chemistry; CHEM/MB&B325 Introduction to Biomolecular Structure; CHEM385, Advanced Biochemistry: Enzyme Kinetics; CHEM/MB&B386 Biological Thermodynamics; CHEM387 Enzyme Mechanisms; CHEM390/MB&B340 Physical Principles in Biochemistry; any other chemistry courses, 300-level or higher, or MB&B208 Molecular Biology. One upper-level MB&B course can be used as an elective upon prior approval by the faculty advisor. (Note, however, that only one MB&B course, including MB&B208, not cross-listed with chemistry, may count as an elective toward the major.) Also required is MATH117 or MATH121, preferably the former, or Advanced Placement calculus with an AP score of 4 or 5; MATH118 or MATH122 and a year of physics are recommended. One of the electives may be replaced by two semesters of research (CHEM409/410 Senior Thesis, or CHEM423/424 Undergraduate Advanced Research Seminar). Other seminars or journal clubs cannot be counted as electives. Participation in the weekly biochemistry evening seminar (CHEM587/588) and in research, both during the academic year and over at least one summer, are strongly recommended. Students who intend to be multiple majors are strongly advised to consult with their chemistry advisors at the beginning of their junior year to plan their chemistry program.

Study Abroad.

A semester abroad is possible if adequately planned in advance. Students should discuss plans with their chemistry major advisor.

Capstone Experience.

The recommended capstone experience is research followed by a senior thesis. Successful completion of the integrated lab sequence CHEM375/376 is considered a capstone for those students not doing research in chemistry.

Honors.

Honors are awarded based on the evaluation of senior theses.

Advanced Placement.
  • Students with a Chemistry AP score of 5 may receive 2.00 credits by completing one full year of organic chemistry (CHEM251 and CHEM252) with a minimum grade of B. No credit will be granted if a student completes any of the following courses: CHEM141, CHEM142, CHEM143, or CHEM144.
  • Students with a Chemistry AP score of 5 may receive 1.00 credit by completing CHEM144 with a minimum grade of B. No credit will be granted if a student completes any of the following courses: CHEM141, CHEM142, or CHEM143.
  • Students with a Chemistry AP score of 4 may receive 1.00 credit by either completing CHEM144 with a minimum grade of B or completing a full year of Organic Chemistry (CHEM251 and CHEM252) with a minimum grade of B. No credit will be granted if a student completes any of the following courses: CHEM141, CHEM142, or CHEM143.
International Baccalaureate Credit.
  • Students with a Chemistry IB score of  6 or 7 (Higher Level) may receive 2.00 credits by completing one full year of organic chemistry (CHEM251 and CHEM252) with a minimum grade of B. No credit will be granted if a student completes any of the following courses: CHEM141, CHEM142, CHEM143, or CHEM144.
  • Students with a Chemistry IB score of  6 or 7 (Higher Level) may receive 1.00 credit by completing CHEM144 with a minimum grade of B. No credit will be granted if a students takes either CHEM141, CHEM142, or CHEM143.
  • Students with a Chemistry IB score of 5 (Higher Level) can receive 1.00 credit by either completing CHEM144 with a minimum grade of B or completing a full year of organic Chemistry (CHEM251 and 252) with a minimum grade of B. No credit will be granted if a student completes any of the following courses: CHEM141, CHEM142, or CHEM143.
  • No credit is awarded for a Chemistry IB score of 4.
A-Levels.  
  • Students with a grade of A on the Chemistry A-Levels can receive 1.00 credit by completing CHEM144 with a minimum grade of B or completing the year-long Organic Chemistry (CHEM251 & CHEM252) with a grade of B or higher.  No credit will be granted if the student has completed any of the following courses: CHEM141, CHEM142, or CHEM143.

Special Note: Students with Chemistry AP, IB, or A-Levels scores who intend to major in chemistry should consult with the department chair as soon as possible.

Transfer Credit.
  • General chemistry courses taken at other institutions will usually satisfy the prerequisites for Organic Chemistry (CHEM251) at Wesleyan. Prerequisite override requests and related questions should be directed to the instructor of CHEM251.
  • The instructor of the equivalent Wesleyan course (CHEM141 or CHEM142 for Introductory Chemistry and CHEM251/252 for Organic Chemistry) for the current academic year must approve all transfer of credit requests. Such approvals are solely at his/her discretion.
  • Permission should be requested before the course is taken. The student should submit
    • the "Permission to Transfer Credit from Another College or University" form available on the Dean's Office website (http://www.wesleyan.edu/deans/forms),
    • the syllabus for the course including the name and author (and edition, if relevant) of the text and the outline of the topical coverage of the course,
    • the total number of class hours involved, and
    • the name and contact information for the course instructor.
  • The other institution must offer a chemistry major and the course must be a gateway course to the major.
  • For community colleges and other two-year institutions, a grade of B+ or better is required for transfer credit.
  • Courses taken elsewhere may not be counted toward a chemistry major at Wesleyan (except by special petition to the Curriculum Committee of the Chemistry Department).
Additional Information.

Undergraduate research is an important part of the program for most majors. Wesleyan's small but excellent graduate program makes it possible for majors to work at the cutting edge of discovery in chemistry. Every full-time faculty member is involved in significant research. Undergraduates participating in the departmental research program normally attend a research seminar in their area, and most research groups have weekly meetings to discuss new results. Students involved in significant research have an opportunity to continue in the University's BA/MA program. Interested students apply in their junior or senior year and if accepted, can continue for a year beyond the bachelor's degree and obtain a master's degree in one additional year. The fifth year is tuition free.

Seminars are a vital part of the intellectual life of the Chemistry Department. Weekly departmental seminars on Friday afternoons (CHEM521/522) are followed by refreshments and discussions in the chemistry lounge. Important scientists from other universities and research laboratories are the speakers. In addition, chemistry students and faculty speak at weekly research seminars in chemical physics, organic/inorganic chemistry, and biochemistry. Programs for each semester are available from the chemistry office.