From Hartford and points north:
Interstate 91 south, Exit 22S, to Route 9. Or Interstate 84 west, Exit 39A to Route 9. From Route 9. take exit 15, Washington Street. Go straight a few blocks and turn left onto High Street. Take the third left onto Williams Street and park in Lot B.

From New Haven and points south:
Interstates 95 and 91, exit 18 or the Merritt/Wilbur Cross Parkway (Route 15) to Route 66 east and follow the signs to Wesleyan.

From Waterbury and points west:
Interstate 84 east to Interstate 691 east to Route 66 east and follow the signs to Middletown and Wesleyan.

From New London:
Interstate 95 south to Route 9 north and follow the signs.

From Boston and points northeast:
Massachusetts Turnpike (Interstate 90) west to Interstate 84 west to Hartford. Take Exit 39A to Route 9. From Route 9 take exit 15, Washington Street. Go straight a few blocks and turn left onto High Street. Take the third left onto Williams Street and park in Lot B.
Or Interstate 95 south through Providence to Route 9 north (approximately 26 miles) and follow the signs to Wesleyan.