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The department is housed in a modern air-conditioned building. Major items of equipment include an Applied Biosystems DNA synthesizer, gel scanning densitometer, Evans and Sutherland Picture System 350, Varian 400 and 500 MHz nuclear magnetic resonance spectrometers, laser Raman spectrometer with UV resonance Raman capability, several UV-visible Spectrophotometers, a stopped flow kinetics system, two high-performance liquid chromatography systems, two transmission microscopes and one scanning electron microscope, several scintillation counters and several preparative ultracentrifuges. Specialized facilities include cold rooms and other constant temperature rooms, environmental chambers and darkrooms with XOMAT. There are computers (IBM and Maclntosh) available in the Graduate Computer room and in the laboratories of the various faculty members for teaching, research, and word processing.FACILITIES: The department is housed in a modern air-conditioned building. Major items of instrumentation for molecular biological analysis include an Applied Biosystems DNA synthesizer, a microarray hybridization chamber, a Perkin-Elmer real time PCR machine, a gel-scanning densitometer/phosphorimager, and an Evans and Sutherland Picture System 350 for visualizing ethidium bromide-stained gels. Analytical instrumentation includes Varian 400 and 500 MHz nuclear magnetic resonance (NMR) spectrometers, a laser Raman spectrometer with UV resonance Raman capability, a time-correlated single photon counting fluorescence setup, a ThermoElectron Deca XP Plus ion trap mass spectrometer equipped for reversed-phase electrospray tandem mass spectrometry, a Brechbuehler helium pressure cell for loading microcapillary columns, several UV-visible spectrophotometers, a stopped flow kinetics system, two high-performance liquid chromatography systems, two standard steady-state fluorometers and a Jasco circular dichroism (CD) spectrometer. Cell biological imaging equipment includes a Zeiss Axioplan fluorescence microscope equipped with CFP/YFP/GFP/Rhodamine filter sets and a Zeiss MRM Digital camera, a Zeiss confocal microscope and digital camera, and transmission and scannning electron microscopes. Additional major equipment includes several scintillation counters, multiple preparative ultracentrifuges, a fermenter, environmental chambers, multiple cold rooms, and a photographic darkroom equipped with an XOMAT film developer. There are multiple computers throughout the building available in the graduate computer room and in faculty member laboratories.