Philip Bolton |
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| 1979-1995
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Philip
Bolton attended Michigan State University, going on to the University of
California, San Diego where he received his Ph.D. in chemical physics,
working with Professor David R. Kearns on the structure of tRNA. He stayed
on as Professor Kearns' postdoctoral fellow for two years, then worked for
one year with Professor Thomas L. James at the University of California,
San Francisco, studying the conformational fluctuations of RNA and DNA.
In
1979, Bolton joined the faculty of Wesleyan University and began working
with two-dimensional nuclear magnetic resonance. His current research
continues the study of the structures of quadruplex DNAs formed by aptamer,
telomere and triplet DNAs. He is now looking at drug molecules which
specifically bind to quadruplex DNAs, how potassium binding controls
quadruplex structure and how loop length and composition affects
quadruplex DNA structure. Bolton served as Chair of the Chemistry
Department from 1995-1997. In addition to authoring over 100 articles for
peer-reviewed scientific publications, he has participated in a number of
site visits for the National Institutes of Health and the National Cancer
Institute. He has also served on a number of study sections for NIH and
the American Cancer Society. |
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