Publications since
1985 1.
P. H. Bolton, “Image Processing of Two-Dimensional
NMR Data.” J. Magn. Reson. 64, 352-355
(1985).
2.
P. H. Bolton, “Magnetic Resonance Imaging Using Flip
Angle Gradients.” J. Magn. Reson. 63,
620-621 (1985).
3.
P. H. Bolton, “Refocusing and Suppression of
Neighbors in Heteronuclear Relay/-Transfer
Spectroscopy.” J. Magn. Reson. 63,
225-229 (1985).
4.
P. H. Bolton, “Heteronuclear Relay Transfer
Spectroscopy with Proton Detection” J. Magn.
Reson. 62, 143-146 (1985).
5.
P. H. Bolton, “Decoupling of Non-Equilibrium Spin
Systems.” J. Magn. Reson. 62, 163-166
(1985).
6.
W. Masseski, Jr., P. H. Bolton, “Quantitative
Analysis of Nuclear Overhauser Effects.” J. Magn.
Reson. 65, 526-530 (1985).
7.
P. H. Bolton, “Image Analysis of Proton
Two-Dimensional Chemical Shift Correlation Spectra by
Application of Symmetry Rules.” J. Magn. Reson.
70, 344-349 (1986).
8.
P. H. Bolton, “Enhancement of Two-Dimensional
Spectra by Application of Symmetry Rules: INADEQUATE as
an Example.” J. Magn. Reson. 68,
180-184 (1986).
9.
P. J. Giammateo, P. H. Bolton, A. J. Stipanovic,
“Characterization of Conformational Changes in
Polysaccharides Using Two-Dimensional NMR
Spectroscopy.” Polym. Mater. Sci. Eng. 54,
650-655 (1986).
10.
D. J. Kerwood, P. H. Bolton, “Low Field NMR.”
J. Magn. Reson. 68, 588-592 (1986).
11.
J. A. Wilde, P. H. Bolton, “Suppression of
Homonuclear Couplings in Homonuclear Multiple Quantum
Spectroscopy.” J. Magn. Reson. 67,
570-574 (1986).
12.
J. A. Wilde, P. H. Bolton, N. J. Stolowich, J. A. Gerlt,
“A General Method for the Observation of Selected
Proton NMR Resonances of Proteins.” J. Magn.
Reson. 68, 168-169 (1986).
13.
D. W. Hibler, N. J. Stolowich, M. A. Reynolds, J. A.
Gerlt, J. A. Wilde, P. H. Bolton, "Site-directed
Mutants of Staphylococcal Nuclease. Detection and
Localization by Proton NMR Spectroscopy of Conformational
Changes Accompanying Substitutions for Glutamic
Acid-43.” Biochemistry 26, 6278-6286
(1987).
14.
M. Manoharan, J. A. Gerlt, J. A. Wilde, J. M. Withka, P.
H. Bolton, “Coexistence of Conformations in a DNA
Heteroduplex Revealed by Site Specific Labeling with
Carbon-13 Labeled Nucleotides.” J. Am. Chem. Soc.
109, 7217-7219 (1987).
15.
M. Manoharan, A. Mazumder, S. C. Ransom, J. A. Gerlt, P.
H. Bolton, “Mechanism of UV Endonuclease V Cleavage
of Abasic Sites in DNA Determined by Carbon-13
Labeling.” J. Am. Chem. Soc. 110,
2690-2691 (1988).
16.
M. Manoharan, S. C. Ransom, A. Mazumder, J. A. Gerlt, J.
A. Wilde, J. M. Withka, P. H. Bolton, “The
Characterization of Abasic Sites in DNA Heteroduplexes
and Their Characterization by Site Specific Labeling with
Carbon-13.” J. Am. Chem. Soc. 110,
1620-1622 (1988).
17.
S. M. Stanzyk, P. H. Bolton, M. Dell’Acqua, T.
Pourmotabbed, J. A. Gerlt, “Direct Observation of
Multiple Environments for the Hd but not the He Proton of
a Histidine Residue in Staphylococcal
Nuclease.” J. Am. Chem. Soc. 110,
7908-7910 (1988).
18.
J. A. Wilde, P. H. Bolton, M. Dell’Acqua, T.
Pourmotabbed, D. W. Hibler, J. A. Gerlt,
“Identification of Residues Involved in a
Conformational Change Accompanying Substitutions for
Glutamate 43 in Staphylococcal Nuclease.” Biochemistry
27, 4127-4132 (1988).
19.
J. A. Wilde, P. H. Bolton, D. W. Hibler, L. Harpold, T.
Pourmotabbed, M. Dell’Acqua, J. A. Gerlt,
“Isotopic Labeling with Hydrogen-2 and Carbon-13 to
Compare the Conformations of Proteins and Mutants
Generated by Site Directed Mutagensis. I.” Methods
Enzymol. 177, 74-86 (1989).
20.
Mazumder, J. A. Gerlt, L. Rabow, J. Stubbe, P. H. Bolton,
“UV Endonuc-lease V from Bacteriophage T4 Catalyses
DNA Strand Cleavage at Aldehydic Abasic Sites by a Syn
ß-Elimination Reaction.” J. Am. Chem. Soc. 111,
8209-8030 (1989).
21.
S. M. Stanczyk, P. H. Bolton, M. Dell’Acqua, J. A.
Gerlt, “Observation and Sequence Assignment of a
cis Prolyl Peptide Bond in Unliganded Staphylococcal
Nuclease.” J. Am. Chem. Soc. 111,
8317-8318 (1989).
22.
D. W. Hibler, L. Harpold, T. Pourmotabbed, M.
Dell’Acqua, J. A. Gerlt, J. A. Wilde, P. H. Bolton,
“Isotopic Labeling with Hydrogen-2 and Carbon-13 to
Compare the Conformations of Proteins and Mutants
Generated by Site Directed Mutagenesis. II.” Methods
in Enzymology 177, 282-292 (1989).
23.
J. A. Wilde, P. H. Bolton, M. Manoharan, S. C. Ransom, J.
A. Gerlt, “Characterization of the Equilibrating
Forms of the Aldehydic Abasic Sites in Duplex DNA by
Oxygen-17 NMR.” J. Am. Chem. Soc. 111,
1894-1896 (1989).
24.
P. H. Bolton, “A Primer on Isotopic Labeling in NMR
Investigations of Biopolymers.” Progress in NMR
Spectroscopy 22, 423-452 (1990).
25.
D. W. Hilber, T. Pourmotabbed, M. Dell'Acqua, J. A.
Gerlt, S. M. Stanczyk, P. H. Bolton, P. Loll, E. Lattman,
"Detection of Conformational Changes in Active Site
Mutants of Staphylococcal Nuclease." UCLA Symp.
Mol. Cell. Biol., New Ser. 110, 17-33
(1990).
26.
T. Pourmotabbed, M. Dell’Acqua, J. A. Gerlt, S. M.
Stanczyk, P. H. Bolton, “Kinetic and Conformational
Effects of Lysine Substitutions for Arginines 35 and 87
in the Active Site of Staphylococcal Nuclease.” Biochemistry
29, 3677-3683(1990).
27.
J. M. Withka, S. Swaminathan, P. H. Bolton, “NOEs in
Duplex DNA Depend on Orientations of Internuclear Vectors
to the Symmetry Axis.” J. Magn. Reson. 89,
386-390 (1990).
28.
D. L. Beveridge, S. Swaminathan, G. Ravishanker, J.
Withka, J. Srinivasan, C. Prevost, S. Louise-May, F. M.
DiCapua, P. H. Bolton, "Methodological
Considerations on Molecular Dynamics Simulations of DNA
Oligonucleotides." AIP Conf. Proc. 239,
311-328 (1991).
29.
Mazumder, J. A. Gerlt, M. J. Absalon, J. Stubbe, R. P.
Cunningham, J. A. Withka, P. H. Bolton,
“Stereochemical Studies of the ß-Elimination
Reactions at Aldehydic Abasic Sites in DNA: Endonuclease
III from Escherichia coli, Sodium Hydroxide and
Lys-Trp-Lys.” Biochemistry 30,
1191-1126 (1991).
30.
L. B. Poole, D. A. Loveys, S. P. Hale, J. A. Gerlt, S. M.
Stanzcyk, P. H. Bolton, “Deletion of an W Loop in
the Active Site of Staphylococcal Nuclease. I.
Identification and Effects on Catalysis, Structure and
Stability.” Biochemistry 30, 3621-3627
(1991).
31.
J. M. Withka, S. Swaminathan, D. L. Beveridge, P. H.
Bolton, “Time Dependence of Nuclear Overhauser
Effects of Duplex DNA from Molecular Dynamics
Trajectories.” J. Am. Chem. Soc. 113,
5041-5049 (1991).
32.
J. M. Withka, S. Swaminathan, P. H. Bolton (1991) “A
Critique of the Interpretation of Nuclear Overhauser
Effects of Duplex DNA” NATO ASI Ser., Ser. A 225,
409-420.
33.
J. M. Withka, J. A. Wilde, P. H. Bolton, A. Mazumder, J.
A. Gerlt, “Characterization of Conformational
Features of a DNA Heteroduplex Containing an Aldehydic
Abasic Site.” Biochemistry 30,
9931-9940 (1991).
34.
Goljer, J. M. Withka, J. Y. Kao, P. H. Bolton,
“Effects of the Presence of an Aldehydic Abasic Site
on the Thermal Stability and Rate of Helix Opening and
Closing of Duplex DNA.” Biochemistry 31,
11614-11619 (1992).
35.
S. M. Stanzyck, P. H. Bolton, “Comparison of
Conformational Features of Staphylococcal Nuclease in
Ternary Complexes with pdTp, pdGp and
Nitrophenyl-pdTp.” Biochemistry 31,
6396-6401 (1992).
36.
M. Withka, J. Srinivasan, P. H. Bolton, “Problems
with, and Alternatives to, the NMR R Factor.” J.
Magn. Reson. 98, 611-617 (1992).
37.
M. Withka, S. Swaminathan, J. Srinivasan, D. L.
Beveridge, P. H. Bolton, “Toward a Dynamical
Structure of DNA: Comparison of Theoretical and
Experimental NOE Intensities.” Science 255,
597-599 (1992).
38.
J. Y. Kao, Igor Goljer, Thu A. Phan, P. H. Bolton,
“Characterization of the Effects of a Thymine Glycol
on the Structure, Dynamics and Stability of a Duplex DNA
by NMR.” J. Biol. Chem. 268,
17787-17793 (1993).
39.
Y. Wang, S. H. Krawczyk, N. Bischofberger, S.
Swaminathan, P. H. Bolton, “The Tertiary Structure
of a DNA Aptamer Which Binds to and Inhibits Thrombin
Determined Activity.” Biochemistry 33,
11285-11292 (1993).
40.
K. Y. Wang, S. McGurdy, R. G. Shea, S. Swaminathan, P. H.
Bolton, “A DNA Aptamer Which Binds to, and Inhibits
Thrombin Exhibits New Structural Motif for
DNA.” Biochemistry 32, 1899-1904
(1993).
41.
S. Balasubramanian, R. Nirmala, D. L. Beveridge, P. H.
Bolton, “Comparison of the Carbon-13 Relaxation
Times and Proton Scalar Couplings of BPTI with Values
Predicted by Molecular Dynamics.” J. Magn. Reson.
B 104, 240-249(1993).
42.
K. Y. Wang, I. Goljer, P. H. Bolton, “Assignments
and Structural Information on Nucleic Acids via PHH
Correlations.” J. Magn. Reson. B 103,
192-196 (1994).
43.
K. Y. Wang, S. Swaminathan, P. H. Bolton “Tertiary
Structure Motif of Oxytricha Telomere DNA.” Biochemistry
33, 7517-7527, (1994).
44.
S. Balasubramanian, R. W. Beger, S. M. Bennett, D. W.
Mosbaugh, P. H. Bolton “Secondary Structure of
Uracil Glycosylase Inhibitor Protein.” J. Biol.
Chem. 270, 296-303, (1995).
45.
R. W. Beger, S. Balasubramanian, S. M. Bennett, D. W.
Mosbaugh, P. H. Bolton,“Tertiary Structure of Uracil
Glycosylase Inhibitor Protein.” J. Biol. Chem.
270, 16840-16847 (1995) .
46.
Goljer, S. Kumar, P. H. Bolton, “Refined Solution
Structure of a DNA Heteroduplex Containing an Aldehydic
Abasic Site.” J. Biol. Chem. 270,
22980-22987 (1995).
47.
H. C. Kung, I. Goljer, P. H. Bolton, “Magnetic
Alignment of Duplex and Quadruplex DNAs.” J.
Magn. Reson. B. 109, 323-325
(1995).
48.
Y. Wang, L. Gerena, S. Swaminathan, P. H. Bolton,
“Determination of the Number and Location of the
Manganese Binding Sites of DNA Quadruplexes in Solution
by EPR and NMR.” Nuc. Acids Res. 23
844-848(1995).
49.
A.Young, J. Srinivasan, I. Goljer, S. Kumar, D. L.
Beveridge, P. H. Bolton, “Structure, Determination
and Analysis of Local Bending in an A-tract DNA Duplex:
Comparison of Results from Crystallography, Nuclear
Magnetic Resonance and Molecular Dynamics Simulation on
d(CGCAAAAATGCG).” Methods in Enzymology 261,
121-144 (1995).
50.
T. P. Hilbert, R. J. Boorstein, H. C. Kung, P. H. Bolton,
D. Xing, R. P. Cunningham, G. W. Teebor,
“Purification of a Mammalian Homologue of E. coli
Endonuclease III: Identification of a Bovine Pyrimidine
Hydrate-Thymine Glycol DNA-Glycosylase/AP Lyase by
Irreversible Cross Linking to a Thymine Glycol-Containing
Oligodeoxynucleotide.” Biochemistry 35,
2505-2511 (1996).
51
H. C. Kung, K. Y. Wang, I. Goljer, P. H. Bolton,
“NMR-Based Structural Studies of Damaged DNAs.”
Magnetic Resonance in Chemistry 34,
S47-S54 (1996).
52.
V. Marathias, K. Y. Wang, S. Kumar, T. Pham, S.
Swaminathan, P. H. Bolton, “Determination of
the Number and Location of the Manganese Binding Sites of
DNA Quadruplexes in Solution by EPR and NMR in the
Presence and Absence of Thrombin.” J. Mol.
Biol. 260, 378-394 (1996).
53.
S. J. F. Vincent, C. Zwahlen, P. H. Bolton, T. Logan, G.
Bodenhausen, “Measurement of Cross-Relaxation
between Amide Protons in 15N Enriched Proteins with
Suppression of Spin Diffusion.” J. Am. Chem.
Soc. 116, 3531-3532(1996).
54.
R. D. Beger, P. H. Bolton, “Protein f and y Dihedral
Restraints Determined from Multidimensional Hypersurface
Correlations of Backbone Chemical Shifts and Their Use in
the Determination of Protein Tertiary Structures.” J.
Biomolecular NMR 10,129-142
(1997).
55.
H. C. Kung, R. D. Beger, S. A. Parker, P. H. Bolton,
"Refinement of the Solution Structures of Damaged
DNAs." Book of Abstracts, 213th ACS National
Meeting, San Francisco, April 13-17, COMP-264
(1997).
56.
H. C. Kung, P. H. Bolton, “Structure of a Duplex DNA
containing a Thymine Glycol Residue in Solution.”J.
Biol. Chem. 272,
9227-9236(1997).
57.
J. Lundquist, R. D. Beger, S. E. Bennett, P. H. Bolton,
D. W. Mosbaugh, “Site-directed Mutagenesis and
Characterization of Uracil-DNA Glycosylase Inhibitor
Protein: Role of Specific Carboxylic Amino Acids in
Complex Formation with Escherichia coli Uracil-DNA
Glycosylase.” J. Biol. Chem. 272,
21408-21419 (1997).
58.
T. Reardon, T. Bessho, H. C. Kung, P. H. Bolton, A.
Sancar, “In Vitro Repair of Oxidative DNA Damage by
Human Nucleotide Excision Repair System: Possible
Explanation for Neurodegen-eration in Xeroderma
pigmentosum Patients.” Proc. National Acad. Sci.
USA 94, 9463-9468 (1997).
59.
Y. Wang, S. A. Parker, I. Goljer, P. H. Bolton
“Solution Structure of a Duplex DNA with an Abasic
Site in a dA Tract.” Biochemistry
39, 11629-11639, (1997).
60.
H. Arthanari, S. Basu, T. L. Kawano, P. H. Bolton,
“Fluorescent Dyes Specific for Quadruplex DNA.”
Nuc. Acids Res. 26, 3724-3728
(1998).
61.
R. D. Beger, H. B. Arthanari, S. Basu, P. H. Bolton,
“Interresidue Quiet NOEs for DNA Structural
Studies.” J. Magn. Reson. 132,
34-40 (1998).
62.
R. D. Beger, P. H. Bolton, “Structures of Apurinic
and Apyrimidinic Sites in Duplex DNA.” J. Biol.
Chem. 273, 15565-15573
(1998).
63.
R. D. Beger, V. M. Marathias, B. F. Volkman, P. H.
Bolton, “Determination of Internuclear Angles of DNA
Using Paramagnetic Assisted Magnetic Alignment” J.
Magn. Reson. 135, 256-259
(1998).
64.
B. Jerkovic, H. C. Kung, P. H. Bolton, “Purification
of Thymine Glycol DNAs and Nucleosides Using Boronate
Chromatography.” Analytical Biochemistry 255,
90-94 (1998).
65.
J. M. McNulty, B. Jerkovic, P. H. Bolton, S. Basu,
“Replication Inhibition and Miscoding Properties of
DNA Templates Containing a Site Specific cis-Thymine
Glycol or Urea Residue.” Chem. Res. Toxicology
11, 666-673 (1998).
66.
H. Arthanari, P. H. Bolton, "Porphyrins can Catalyze
the Interconversion of DNA Quadruplex Structural
Types." Anticancer Drug Des. 14,
317-326 (1999).
67.
A. Klungland, M. Höss, D. Gunz, A. Constantinou, S. G.
Clarkson, P. W. Doetsch, P. H. Bolton, R. D. Wood, T.
Lindahl, “Base Excision Repair of Oxidative DNA
Damage Activated by XPG Protein.” Molec. Cell.
3, 33-42 (1999).
68.
V. M. Marathias, P. H. Bolton, “Determinants of DNA
Quadruplex Structural Type: Sequence and Potassium
Binding.” Biochemistry 38,
4355-4364 (1999).
69.
V. M. Marathias, B. Jerkovic, P. H. Bolton, “Damage
Increases the Flexibility of Duplex DNA.” Nuc.
Acids Res. 227, 1854-1858
(1999).
70.
V. M. Marathias, M. J. Sawicki, P. H. Bolton,
"6-Thioguanine Alters the Structure and Stability of
Duplex DNA and Inhibits Quadruplex DNA Formation." Nucleic
Acids Res. 27, 2860-2867
(1999).
71.
H. Arthanari, B. Jerkovic, A. A. Fondren, P. H. Bolton,
"Detection of Quadruplex DNA by Selective
Fluorescent Staining of Native Gels." submitted
(2000).
72.
B. Jerkovic, P. H. Bolton, "The Curvature of dA
Tracts is Temperature Dependent [In Process
Citation]." Biochemistry 39,
12121-12127 (2000).
73.
V. M. Marathias, P. H. Bolton, "Structures of the
Potassium Saturated, 2:1, and Intermediate, 1:1, Forms of
a Quadruplex DNA." Nucl. Acids. Res. 28,
1969-1977 (2000).
74.
V. M. Marathias, B. Jerkovic, H.Arthanari, P. H. Bolton,
"Flexibility and Curvature of Duplex DNA Containing
Mismatched Sites as a Function of Temperature." Biochemistry
39, 153-160 (2000).
75.
H. Arthanari, P. H. Bolton, "Functional and
Dysfunctional Roles of Quadruplex DNA." Chem
Biol. 8, 221-230 (2001).
76.
B. Jerkovic, P.H. Bolton, "Magnesium increases the
curvature of duplex DNA that contains dA tracts." Biochemistry
40, 9406-9411 (2001).
77.
J.C. Shiels, B. Jerkovic, A.M. Baranger, P.H. Bolton,
"RNA-DNA hybrids containing damaged DNA are
substrates from RNase." Bioorg Med Chem Lett
11, 2623-2626 (2001).
78.
H. Arthanari, P.H Bolton, "Did quadruplex DNA play a
role in the evolution of the eukaryotic linear
chromosome?" Mini Reve Med Chemistry 3,
1-9 (2003).
79.
H. Arthanari, K.J. McConnell, R. Beger, M.A. Young,, D.L.
Beveridge, P.H. Bolton, "Assessment of the molecular
dynamics structure of DNA in solution based on calculated
and observed NMR NOESY volumes and dihedral angles from
scalar coupling constants." Biopolymers 68,
3-15 (2003).
80.
H. Anthanari, K. Wojtuszewski, I. Mukerji, P.H. Bolton,
"Effects of HU binding on the equilibrium
cyclization of mismatched, curved, and normal DNA." Biophys.
86, 1625-1631 (2004).
81.
H. Arthanari, I. Rujan, P.H. Bolton, "Porphyrins
binds to parallel strand quadruplex DNAs." submitted
(2004).
82.
I.N. Rujan, J.C. Meleney, P.H. Bolton, et al.,
"Vertebrate telomere repeat DNAs favor external loop
propeller quadruplex structure in the presence of high
concentrations of potassium." Nucleic Acids
Research 33, 2002-2031 (2005).