Research Articles: 1.
S.S.Patel, M.M.Hingorani, "Oligomeric structure of
bacteriophage T7 primase/helicase proteins." J.
Biol. Chem. 268, 10668-10675 (1993).
2.
M.M.Hingorani, S.S. Patel, "Interactions of
bacteriophage T7 primase/helicase protein with
single-stranded and double-stranded DNAs." Biochemistry
32, 12478-12487 (1993).
3.
S.S. Patel, M.M, Hingorani, W.M. Ng, "The K318A
mutant of bacteriophage T7 primase-helicase protein is
deficient in helicase but not primase activity and
inhibits primase-helicase protein wild-type activities by
hetero-oligomer formation." Biochemistry 33,
7857-7868 (1994).
4.
S.S. Patel, M.M. Hingorani, "Nucleotide binding
studies of bacteriophage T7 DNA helicase-primase
protein." Biophysical Journal 68,
186s-190s (1995).
5.
E.H. Egelman, X. Yu, R. Wild, M.M. Hingorani, S.S. Patel,
"T7 helicase/primase proteins form rings around
single-stranded DNA that suggest a general structure for
hexameric helicases." Proc. Natl. Acad. Sci. USA 92,
3869-3873 (1995).
6.
M.M. Hingorani, S.S. Patel, "Cooperative
interactions of nucleotide ligands are linked to
oligomerization and DNA binding in bacteriophage T7 gene
4 helicases." Biochemistry 35,
2218-28 (1996).
7.
X. Yu, M.M. Hingorani, S.S. Patel, E.H. Egelman,
"DNA is bound in the central hole to one or two
subunits of the T7 DNA helicase." Nature
Structural Biology 3, 740-743
(1996).
8.
M.M. Hingorani, M.T. Washington, K.C. Moore, S.S. Patel,
"The dTTPase mechanism of T7 DNA helicase resembles
the binding change mechanism of the F1-ATPase."
Proc. Natl. Acad. Sci. USA 94,
5012-5017 (1997).
9.
M.M.
Hingorani, M. O'Donnell, " Toroidal proteins:
running rings around DNA." Current Biology 8,
R83-R86
(1998).
10. M.M.
Hingorani, M. O'Donnell, "ATP binding to the E.
coli clamp loader powers opening of the ring-shaped
clamp of DNA polymerase III holoenzyme." J. Biol.
Chem. 273, 24550-24563 (1998).
11.
B. Ason, J.G. Bertram, M.M. Hingorani, J.M. Beechem, M.
O'Donnell, M.F. Goodman, L.B. Bloom, "A model for E.
coli DNA polymerase III holoenzyme assembly at
primer/template ends: DNA triggers a change in binding
specificity of the g complex clamp loader." J.
Biol. Chem. 275, 3006-3015 (1999) .
12.
J. Turner, M.M. Hingorani, Z. Kelman, M. O'Donnell,
"The internal workings of a DNA polymerase
clamp-loading machine." EMBO J 18,
771-783 (1999).
13.
M.M. Hingorani, L.B. Bloom, M.F. Goodman, M. O'Donnell,
"Division of labor-sequential ATP hydrolysis drives
assembly of a DNA polymerase sliding clamp around
DNA." EMBO J 18, 5131-5144
(1999).
14..
M.M. Hingorani, "S(t)imulaing science." Science
246, 2466-2467 (1999).
15.
M.M. Hingorani, M. O'Donnell, " Sliding clamps: A
(tail)ored fit." Current Biology 10,
R25-R29 (2000).
16.
M.M. Hingorani,M. O'Donnell, "A tale of toroids in
DNA metabolism." Nature Reviews Cell and
Molecular Biology 1, 22-30 (2000).
17.
M.M. Hingorani, M. O'Donnell, "DNA polymerase
structure and mechanisms." Current Organic
Chemistry 4, 887-913 (2000).
18.
J.G. Bertram, L.B. Bloom, M.M. Hingorani, J.M. Beechem,
M. O'Donnell, M.F. Goodman, "Molecular mechanism and
energetics of clamp assembly in Escherichia coli.
The role of ATP hydrolysis when g complex loads bon DNA. J.
Biol. Chem. 275, 28413-28420 (2000)
.
19.
F. P. Leu, M.M. Hingorani, J. Turner, J., M.E. O'Donnell,
“The d subunit of DNA polymerase III holoenzyme
serves as the sliding clamp unloader in E. coli.”
J. Biol. Chem. 275, 34609-34618
(2000).
20.
J. Stewart, M.M. Hingorani, Z. Kelman, M.E.
O’Donnell, “Mechanism of bClamp Opening by the
dSubunit of E. coli DNA Polymerase III
Holoenzyme.” J. Biol. Chem. 276,
19182-19189 (2001) .
21.
D. Jeruzalmi, O. Yurieva, Y. Zhao, M. Young, J. Stewart,
M. M. Hingorani, M. O’Donnell, J. Kuriyan,
“Mechanism of Processivity Clamp Opening by the d-Subunit
Wrench of the Clamp Loader Complex of E. coli DNA
Polymerase III.” Cell 106,
417-428 (2001).
22.
M.M. Coman, M.M. Hingorani, "On the specificity of
interaction between S. cervesiae clamp loader, RFC, and
primed DNA during DNA replication." J. Biol.
Chem. 277, 47213-47224 (2002).
23.
B. Ason, R. Handayani, C. Williams, J. Bertram, M.M.
Hingorani, M. O'Donnell, M. Goodman, L.B. Bloom,
"Mechanism of loading the E. coli DNA
polymerase III b sliding clamp
on DNA." J. Biol. Chem 278,
10033-10040 (2003).
24.
J.F. Finkelstein, E.A. Antony, M.M. Hingorani, M.
O'Donnell, "Over-production and analysis of
eukaryotic multi-protein complexes in E. coli using
a dual vector strategy." Analytical Biochemistry
319, 78-87 (2003).
25.
E.A. Antony, M.M. Hingorani, "Mismatch
recognition-coupled stablization of Msh2-Msh6 in an
ATP-bound state at initiation of DNA mismatch
repair." Biochemistry 42,
7682-7693 (2003).
26.
N. Yao, L. Coryell, D. Zhang, R.E. Georgescu, J.
Finkelstein, M.M. Coman, M.M. Hingorani, M. O'Donnell,
"Replication Factor C clamp loader subunit
arrangement within the circular pentamer and its
attachment points to Proliferating Cell Nuclear
Antigen." Journal of Biological Chemistry 278,
50744-50754 (2003).
27.
M.M. Hingoran, M. O'Donnell, "DNA Elongation"
in The Bacterial Chromosome (N. Pat Higgins,
ed.), ASM Press, Washington, D.C. (2004).
28.
M.M. Coman, M. Jin, R. Ceapa, J. Finkelstein, M.
O'Donnell, B.T. Chait, M.M. Hingorani, "Dual
functions, clamp opening and primer-template recognition,
define a clamp loader subunit." Journal of
Molecular Biology 342, 1457-1469
(2004).
29.
E.A. Antony, M.M.Hingorani, "Asymmetric ATP binding
and hydrolysis activity of the Thermus aquaticus
MutS dimer is key to modulation of its interactions with
mismatched DNA." Biochemistry 43,
13115-13128 (2004).
30.
C.R. Zito*, E.A. Antony*, J.F. Hunt, D.B. Oliver, M.M.
Hingorani, "Role of a conserved glutamate residue in
E. coli SecA ATPase mechanism." Journal
of Biological Chemistry 280,
14611-14619 (2005). *These authors
contributed equally to the research.