Summer 2008
Fully Enrolled

SCIE 612
Neuroscience and Behavior

Naegele,Janice R; Lombroso,Paul

06/23/2008 - 08/01/2008
Tuesday & Thursday 06:00 PM - 08:30 PM

Science Tower 121

Neuroscience is a highly interdisciplinary field drawing from diverse disciplines. This course introduces key concepts for understanding the functional organization of the brain and how it develops in embryonic and postnatal life. Lectures highlight how sensory experience and neural activity shape brain function and behavior throughout life. Case studies will be used to illustrate neurological disorders including vision loss, epilepsy, Alzheimer's disease, phantom limbs, and autism spectrum disorders. Hands-on work with human brain models will reinforce readings and lectures.

Online hybrid course: Approximately 25% of the meeting time for this course will occur through an online format. The class will meet in person on July 2, 9, 11, 16, 18, 23, 25, and July 30.

The first online class on 6/27/2012 will consist of a powerpoint lecture in several parts. You can watch this at your convenience and take the on-line test before our first in-person class meeting on July 2, 2012. These should be available a few days before the official beginning of the course.

The second online class (Class #3) will consist of a powerpoint lecture in several parts and an additional on-line learning assessment that you complete. This lecture and on-line assessment will be available by July 2 and you have until July 9 to complete it.

Student oral presentations will occur in class on July 30. There will be online assessment of core concept mastery during the period from June 27-July 4.

Readings will come from Scientific American, Discover, and New Yorker Magazine, as well as from Brain Facts: A Primer on the Brain and Nervous System; Purves and Lotto, Why We See What We Do; and Sapolsky, The Trouble with Testosterone and Why Zebras Don't Get Ulcers.

Course requirements include class participation, written assignments, an exam, and a final project.

A syllabus for this course is available at:
Course Syllabus

Janice Naegele (B.A., Mount Holyoke College; Ph.D., Massachusetts Institute of Technology) is professor and chair of biology, and professor of neuroscience and behavior. Current work in the Naegele Lab focuses on the link between cell death, neurogenesis, and DNA repair in the developing and adult cerebral cortex and hippocampus. Recent publications include (with Choi, Lin, Lee, Kurup, Cho, Lombroso, and Obrietan) Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase (Journal of Neuroscience, 2007), Neuroprotective strategies to avert seizure-induced neurodegeneration in epilepsy (Epilepsia, 2007), and (with Navarro-Quiroga, Hernandez-Valdes, and Lin) Postnatal cellular contributions of the hippocampus subventricular zone to the dentate gyrus, corpus callosum, fimbria, and cerebral cortex (Journal of Comparative Neurology, 2006). Click here for more information about Janice Naegele.

Paul Lombroso (B.A., Harvard College; M.D., Albert Einstein School of Medicine) is Elizabeth Mear and House Jameson Professor for the Child Study Center at Yale University, School of Medicine. He is a molecular biologist and child psychiatrist whose recent publications include (with Paul, Nairn, and Wang) NMDA-mediated activation of the protein tyrosine phosphatase, STEP, regulates the duration of ERK signaling (Nature Neuroscience, 2003), and (with Karasawa, Yokokura, and Kitajewski) Frizzled-9 is activated by Wnt-2 and functions in Wnt/b-catenin signalling (Journal of Biological Chemistry, 2002). Click here for more information about Paul Lombroso.


Consent of Instructor Required: No

Format: Seminar

Level: GLSP Credits: 3 Enrollment Limit: 18

Texts to purchase for this course:

See course syllabus for more information regarding course readings.

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