Summer 2005

SCIE 634
Biology of Aging

Wolfe,Jason S.

06/27/2005 - 08/10/2005
Monday & Wednesday 09:30 AM - 12:00 PM

Shanklin 201

Research on the biology of aging has advanced considerably in the past few decades, at the same time as the population of the United States has aged. This new research is enhancing the quality of life among the elderly as well as extending the maximum-life span.

This course will examine various lines of research on the biology of aging using model systems such as yeast, nematodes, and mice, and will explore various theories of aging, including cellular senescence, regulated cell death, somatic mutation, free radicals, endocrine decline, and immunosenescence. The biological basis of some age-related diseases such as Alzheimer's Disease, atherosclerosis, and cancer will also be discussed. Finally, throughout the course, we will consider some of the ethical and social implications of increased longevity and disease treatment.

Readings will include selections from textbooks on aging, scientific articles, and current magazine and newspaper articles.

Evaluations will be based on class participation and two term papers.

Field trips to some of Middletown's organizations that work with the elderly may be possible.

Jason Wolfe (B.A. Rutgers University; Ph.D. University of California, Berkeley) is professor of biology and primary or contributing author of 45 publications. His laboratory is involved in research on cell reproduction, cell interactions, and cell death. The team has been examining such topics as cell recognition and adhesion, as well as cell differentiation and morphogenesis, by studying sexual interaction in the single-celled organism, Tetrahymena thermophila. In recent years, the team has begun to exploit a novel developmental property of this cell-type to also study the regulation of nuclear death as it relates to the process of apoptosis, or programmed cell death, and autophagy, or self-digestion. Click here for more information about Jason Wolfe.


Consent of Instructor Required: No

Format: Seminar

Level: GLSP Credits: 3 Enrollment Limit: 18

Texts to purchase for this course:

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