Summer 2005

SCIE 680
Genetics Laboratory

McAlear,Michael A.

06/20/2005 - 06/25/2005
Note: Special Schedule -

Science Tower 90A

While the science of genetics has been practiced for thousands of years (animal breeding, crop selection), it is only in the last 60 years or so that we have begun to understand how genetic traits are encoded and passed on through the generations. In particular, over the past few decades technological advances in the molecular biosciences have led scientists to profound discoveries concerning how genetic systems work. We have also developed sophisticated tools and techniques for manipulating genetic systems. This will be an intensive and comprehensive genetics laboratory course that will include experiments in both prokaryotic and eukaryotic systems. Students will gain first hand laboratory experience with experiments involving Mendelian inheritance, dominant and recessive traits, transformations, genetic recombination, and the phenotypic expression of mutant genes. E. coli and budding yeast will be used as model prokaryotic and eukaryotic organisms. The days will include laboratory exercises as well as lectures on the relevant background material, including basic molecular genetics, genes and genomes, and introductory bioinformatics.

Readings will include excerpts from Watson, Gilman, Witkowski, and Zoller, Recombinant DNA.

The course will be well-suited for high school science teachers, and efforts will be made to cover material and topics that could be used in a high school classroom setting.

The class schedule is 9 a.m.-5 p.m. on Monday, Tuesday, Thursday, and Friday. Wednesday and Saturday class days are from 9 a.m.-1p.m. Enrollment is limited to 10 students. Additional fee: $75.

Registration and withdrawal deadline: Friday, May 27, 2005.

Michael McAlear (B.S., Ph.D. McGill University) is associate professor of molecular biology and biochemistry. His research focuses on DNA replication, DNA repair, and rRNA metabolism in yeast, and his articles have appeared in the journals Biochemistry, Molecular and Cellular Biology, Genetics, Molecular Genetics, and the Journal of Biological Chemistry. Click here for more information about Michael McAlear.


Consent of Instructor Required: No

Format: Laboratory

Level: GLSP Credits: 3 Enrollment Limit: 10

Texts to purchase for this course:

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