Summer 2007

SCIE 680
Molecular Biology Laboratory

McAlear,Michael A.

06/18/2007 - 06/23/2007
Note: Special Schedule -

Science Tower 90A; Science Tower 0101

Special Schedule: One-week immersion, August 10 - 15
9 am-5 pm (Mon, Tues, Thurs, & Fri); 9 am-1 pm (Wed & Sat)

Molecular biology is a fast-moving, experimentally-driven discipline that continues to shed light on the underlying mechanisms that drive biological processes. Over the past few decades, technological advances in the molecular biosciences have led scientists to profound discoveries in disciplines ranging from anthropology to veterinary sciences. This will be an intensive and comprehensive laboratory course that covers several of the experimental techniques used in modern molecular biology. Students will gain firsthand laboratory experience in the use of recombinant DNA technology, protein expression and purification, gel electrophoresis, the polymerase chain reaction, and microbial genetics (the relationship between genotype and phenotype). E. coli and budding yeast will be used as model prokaryotic and eukaryotic organisms. The days will include laboratory exercises as well as lectures on the relevant background material, including basic molecular biology, genetics, genes and genomes, and introductory bioinformatics.

Readings will be excerpts from Watson, Gilman, Witkowski and Zoller, Recombinant DNA, (W. H. Freeman & Co.).

The course will be well suited for science enthusiasts who possess the foundational vocabulary of biology, and for high school science teachers. The course will cover material and topics that may be adapted to the high school classroom setting.

The course schedule is as follows: 9 AM-5 PM (Monday, Tuesday, Thursday, & Friday); 9 AM-1 PM (Wednesday & Saturday).

Enrollment is limited to 12 students.

Additional fee: $115

A syllabus for this course is available at:
Course Syllabus

Michael McAlear (B.S., Ph.D. McGill University) is associate professor of molecular biology and biochemistry. His research focuses on DNA replication, DNA repair, and rRNA metabolism in yeast, and his articles have appeared in the journals Biochemistry, Molecular and Cellular Biology, Genetics, Molecular Genetics, and the Journal of Biological Chemistry. Click here for more information about Michael McAlear.


Consent of Instructor Required: No

Format: Laboratory

Level: GLSP Credits: 3 Enrollment Limit: 10

Texts to purchase for this course:

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