Summer 2005

SCIE 682
Microscopic Cell Anatomy and Physiology

Marcucci,Melissa Jean

06/27/2005 - 08/10/2005
Tuesday-Thursday -

This course is designed for students interested in gaining an understanding of how cellular structure contributes to function in mammalian organ systems. The model for this course is the human cell. The cell is the fundamental structural and functional unit of which all living organisms are constructed. We will cover the basic biology of the human body with an emphasis on how the specialized cellular organization of human body tissues attributes to optimal physiological function. Each session will be divided into a lecture and a laboratory component. A 75-90 minute lecture on the cell biology and physiology of a particular tissue/system will be followed by a one-hour laboratory exercise using state of the art equipment and cutting-edge technology to further examine the lecture topic microscopically. During the first part of the course, we will emphasize basic structure and function of the cell and its organelles. During the second part, we will cover organization of the cells into tissues and organs. Our goal is to gain an understanding of the structure and function of the normal cell as it behaves in a particular system. This knowledge is essential for understanding the basic cellular mechanisms underlying disease.

Readings will be from Wheater's Functional Histology: A Text and Color Atlas (4th edition) and from a cell biology/physiology textbook to be announced. Students will be assigned advanced readings, and preparation will be assumed for each class. Students will also receive laboratory manuals that will serve as a guide for the laboratory exercises.

A midterm and a final (in class) examination are planned. Examinations will be a combination of written (short answer) and practical utilizing the microscopes.

Melissa Marcucci(B.A., B.S. Boston University; M.Phil., Ph.D. Yale University) is visiting assistant professor of molecular biology and biochemistry. She is co-author of "Amphiphysin participates in the formation of clathrin-coated pits during synaptic vesicle recycling in the lamprey giant axon, "Traffic (2004), and primary author of "Developmental characterization of amphiphysin 2 in skeletal muscle: an integral component of the transverse tubule"(in preparation).


Consent of Instructor Required: No

Format: Seminar

Level: GLSP Credits: 3 Enrollment Limit: 18

Texts to purchase for this course:
Sylvia Mader, UNDERSTANDING HUMAN ANATOMY AND PHYSIOLOGY (McGraw Hill) 5th Edition, Paperback

Barbara Young, WHEATER'S FUNCTIONAL HISTOLOGY (Churchill Livingston) 4th Edition, Paperback


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