Molecular Biophysics is situated at the intersection of molecular biology, chemistry, and physics and defines an interdisciplinary vantage point from which many new and important advances are being made in life science research. Molecular biophysics, as a field of endeavor, is distinguished by analytical and quantitative research inquiry based on molecular and macromolecular structure and spectroscopy, biophysical chemistry, functional bioenergetics, statistical thermodynamics, and molecular dynamics. Opportunities in molecular biophysics are open to students with strong interests and and a solid undergraduate background in chemistry, physics and mathematics.
Protein structures and folding,molecular models of enzyme mechanisms, DNA fine structure and curvature, molecular recognition and the nature of gene expression and regulation are some of the many topics of active research interest in molecular biophysics. Both experimental and theoretical research methods are utilized. In addition to standard biochemical and biophysical techniques, optical and magnetic resonance spectroscopies, x-ray crystallography, microcalorimetry, transient kinetic techniques, statistical mechanics, computer simulations and molecular modeling are included in the repertoire of molecular biophysics researchers. As a consequence of recent advances stemming from the human genome project, the field of bioinformatics finds an increasingly important emphasis in our program.