Wesleyan portrait of Phil  Arevalo

Phil Arevalo

Assistant Professor of the Practice in Biology and CIS

Hall-Atwater Laboratories, 165C
860-685-2080

Assistant Professor of the Practice, Integrative Sciences

parevalo@wesleyan.edu

PHD Massachusetts Institute of Technology
SB Brown University

Phil Arevalo

Dr. Phil Arevalo uses a combination of mathematical modeling and computational tools to reveal the forces that drive the diversification and evolution of microbial genomes. His current research covers two main areas: understanding the interplay between host immune systems and viral evolution, and clarifying the tangled histories of genes in bacterial genomes.

The first area broadly seeks answers to the question: "Why are some people more susceptible to flu than others?" While a vast array of factors is involved, one's own particular history of exposures to different pathogens may play an important role in explaining differences in susceptibility. By combining epidemiological and genomic data, Dr. Arevalo hopes to better understand what causes the different "perspectives" each of our immune systems has.

The second area stems from the observation that bacterial genomes are amazingly dynamic, with genes being lost, gained, and transferred again and again. As a whole, microbial species have access to an extensive toolbox of genes, but no one single strain possesses every single tool. Why are some genes present in all members of a species? Why are other genes only present in a small subset of strains? Using the vast array of bacterial genomes that have been sequenced, we can begin to answer these questions and test the limitations of current genomic theory.

Academic Affiliations

Office Hours

Spring 2024 Office Hours:

Mon. 2:00PM - 3:00PM

Tue. 9:00AM - 10:00AM

Thur. 3:00PM - 4:30PM

Office hours will take place in Hall-Atwater 165C.

Courses

Spring 2024
BIOL 217 - 01
Microbial Genomics & Evolution

BIOL 270 - 01
Systems Biology

BIOL 271 - 01
Systems Biology

CIS 222 - 01
Research Frontiers Sciences II