Biological Chemistry Seminars - Fall 2020
Coordinated by Professor Irina Russu
Professor of Chemistry 

Seminars held virtually on Mondays at 12 PM 
unless otherwise stated
CHEM587 / MB&B587






Sept. 7 Dr. Irina M. Russu Wesleyan University  Introduction and Organization
Sept. 14 Mark Han  Wesleyan University  In Silico Investiagation of Tumor Suppressor p53: the Wild Hunt for Cancer Therapeutics
Sept. 21 No seminar  -- --
Sept. 28* Dr. Tom Broker U. of Alabama Birmingham HPV-Host Cell Interactions and Anti-Viral Drug Discovery in 3D-Tissue Systems
* Dr. Broker is the keynote speaker for the 21st Annual Retreat of the Molecular Biophysics Program. The seminar starts at 2:50 PM.
Oct. 5 Bakar Hassan  Wesleyan University  Characterization of E. coli Heptosyltransferase II
Oct. 12 Nick Wells  Wesleyan University  Common perturbations to maturational free energy in ALS-linked SOD1 mutations
Oct. 19 Jozie Milicaj  Wesleyan University  Addressing the Antibiotic Resistance Problem: Perturbing Lipopolysaccharide Biosynthesis via Inhibition of Heptosyltransferase I
Oct. 26 No seminar -- --
Nov. 2 Joshua Dudley  Wesleyan University  Characterizing Structural Heterogeneity in Computationally Designed Mini Proteins
Nov. 9* Dr. Jason Kahn  U. of Maryland College Park  DNA Flexibility via DNA Looping and High-Throughput Sequencing 
* The seminar starts at 2:50 PM.
Nov. 16 Ben Cowan  Wesleyan University  Visualizing and Analyzing Motional Covariance in Proteins: MD-Sectors and Principle Component Analysis
Nabeel Kemal Wesleyan University  Mapping and Visualizing the Free Energy Landscape of p53 using Vectors
Nov. 23 Thanksgiving Break -- --
Nov. 30 Thanksgiving Break -- --


Biological Chemistry Seminars - Spring 2021
Coordinated by Professor Alison O'Neil
Professor of Chemistry 

Seminars held virtually on Mondays at 12 PM 
unless otherwise stated
CHEM588 / MB&B588





February 15


*Brief Class Meeting*


February 22

Joshua Powell, PhD


Working in Industry Series

March 1

Feodore Price, PhD

5AM Ventures and Harvard University

Working in Industry Series

March 8

Sandra Lopez, PhD

Takeda Pharmaceuticals

Working in Industry Series

March 15

Marisa Plescia

Cosmetic Chemist, Bell Laboratories; Chair, Society of Cosmetic Chemists

Working in Industry Series

March 22

Angelika Rafalowski

Dr. Erika A. Taylor Lab

Expansion and Characterization of the Protocatechuate Dioxygenase Superfamily

March 29

Mikayla Mclaughlin

Dr. Alison O'Neil Lab

Investigation of the Biochemical Landscape, Cellular Environment, and Pathogenicity of SOD1, an ALS Linked Protein

April 5

Eric Zanderigo

Dr. Alison O'Neil Lab

Analysis of the Structure, Propagation, and Motor Neuron-Selective Pathogenicity of Misfolded SOD1 in ALS

April 12

Kat Blejec

Dr. Colin Smith Lab

Elucidating the Allosteric Mechanisms of Increased Signaling Activity Through Mutation of Unregulated H-Ras

April 19

Camille Chossis

Dr. Alison O'Neil Lab

The C9ORF72 mutation and its effect on astrocyte inflammation in a Human stem cell model of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

April 26

Brynn Assignon

Dr. Erika A. Taylor Lab

Taylored Enzymes: Creating Chimeric Protein Libraries for Glycodiversification Through Domain Swapping

May 3

Colleen Castro

Dr. Erika A. Taylor Lab

Computationally and Experimentally Determining Inhibitors of Heptosyltransferase I

May 10

Jacob Greene

Dr. Alison O'Neil Lab

A synthetic portal into the genome enables controlled transgenesis in differentiating human stem cells