SCIE 681
The Genetic Basis of Inherited Disorders

Michael McAlear         

Course Schedule
September 12 Introduction to Cellular and Molecular Biology
Genome: Preface, Ch 1
September 19 Basic Genetics, Genomics
Genome: Ch 3
September 26 Mutations, Epigenetics, Environment
Genome: Ch 5
October 3 Single gene disorders: Cystic Fibrosis, Huntington's Disease
Genome: Ch 4
October 10 Genetic Selection: Sickle Cell Anemia and Malaria
Genome: Ch 9
October 17 Fall Break
October 25 Class Test I
October 31 Cancer, oncogenese, tumor suppressors
Genome: Ch 17
November 7 Cancer cont'd
November 14 Aging, Alzheimer's
Genome: Ch 14, 19
November 21 Heart Disease
November 28 Gene Chips, Gene therapy, and individualized medicine
Genome: Ch 18
December 5 Class Test II
Reading List:
The World of the Cell, 6th Edition by Becker et al.
iGenetics by Peter Russell
Genome: The Autobiography of a Species in 23 Chapters by Matt Ridley

Video: A Question of Genes

Class Test I 25%
Class Test II 25%
Presentation 25%
Paper 25%